High wholesaler Quality and Good Price Mirabegron Pharmaceutical Chemicals for 223673-61-8 with ce certificate top quality low price

Product Description

Product Description
What is Mirabegron?
Mirabegron is for the treatment of urgency, urinary frequency, and urinary urge urinary incontinence associated with overactive bladder (OAB). Mirabegron is synthesized by coupling 4-nitrophenethyl amine to (R)-2-hydroxy-2-phenylacetic acid. The resulting amide is reduced to an amine. The nitro group is then reduced and the resulting is coupled to 2-(2-aminothiazol-4-yl) acetic acid to give mirabegron. Mirabegron has an EC50 of 22 nM (intrinsic activity=0.8) for β3-AR with no detectable activity for β1- andβ2-AR (EC50>10,000 nM). In an anesthetized rat rhythmic bladder contraction model in which bladder contractions are induced by saline, mirabegron at 3 mg/kg iv decreased the frequency of rhythmic bladder contraction without suppressing contraction amplitude. These data suggest that the activation of β3-AR increases bladder capacity without influencing the frequency of bladder contraction.
1.Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
2.Uses for A potent bladder relaxant compound
3.Uses for Potent bladder relaxant and reagent for diabetes remedy.;Labeled Mirabegron, intended for use as an internal standard for the quantification of Mirabegron by GC- or LC-mass spectrometry.

Product Name: Mirabegron
CAS: 223673-61-8
MF: C21H24N4O2S
MW: 396.51
EINECS: 800-126-3
Mol File: 223673-61-8.mol
brand Lingding


Company Information
ZheJiang Lingding CZPT nology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of “focus on products, attentive service”, adhere to the business purpose of “innovation, professional, win-win”, to provide CZPT ers with a full range of meticulous and thoughtful services. We will adhere to the CZPT er’s serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete CZPT er needs.
The company’s products are sold all over the world, mainly exported to the CZPT States, CZPT pe, CZPT Asia, Australia, the Middle CZPT and South Africa and other countries.The company has a strong scientific research and technical team, can provide CZPT ers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of CZPT ers, to meet the challenges of the market.  Welcome domestic and foreign CZPT ers to negotiate.

Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit CZPT website.
 3.API, Intermediate are CZPT , we can offer CZPT Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
Packaging & CZPT

 Q1. Are you a manufacturer?
Answer: Yes, we have CZPT own factory.

Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, CZPT , or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment?
Answer: T/T in CZPT are highly recommended. We can accept CZPT ern CZPT ,
Money Gram and Paypal as well.

Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, CZPT Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find CZPT products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q9.Do you have stock?
Answer:As we know,most CZPT ers prefer stock,so we will try to keep stock for some products.